Kenari Nut Consumption Increases High Density Lipoprotein Levels And Inhibits Low Density Lipoprotein In Rats

Abstract

Introduction: Consumption of tree nuts is associated to the lowering risk of coronary heart disease due to the inhibition of lipid oxidation. Kenari (Canarium indicum) contains bioactive compound which is antioxidant in nature. However, data to support the influence of kenari nut consumption on the lipid oxidation level in serum has not been reported.
Objective: To determine the potential cholesterol-lowering response on eating kenari nut

Methods: In-vivo examination has been conducted in this research. Rats were randomly divided into three groups (n=6 for each). Control group (Group I) fed basic diet for 10 weeks and treated groups fed basic diet plus kenari nut which constituted of 20% (Group II) and 40% (Group III) of daily caloric intake, respectively. Serum total cholesterol, Low-Density Lipoprotein (LDL), High-Density Lipoprotein (HDL), and triglyceride (TG) levels were measured. Data were expressed as mean ± sd. Unpaired student t-test was used to compare differences between control and treatment.

Results: The results of this study showed that the serum total cholesterol of Group I was 114.62±4.61 mg/dL, whereas that of Group II and Group III were 103.16±1.48 mg/dL and 108.17±3.92 mg/dL, respectively. The LDL level of Group I was 27.92±2.11 mg/dL, Group II was 23.87±1.85 mg/dL, and Group III was 20.38±1.66 mg/dL. The HDL levels of each group were measured at 114.68±2.02 mg/dL, 126.76 ±2.63 mg/dL, and 128.44±2.13 mg/dL, respectively. The TG in the serum of Group I, II, and III were 93.16±4.94 mg/dL, 79.35±2.48 mg/dL, and 84.95 ±5.45 mg/dL, respectively. The body weights of all treated groups were the same. Conclusion: The consumption of Kenari nut is valuable to health due to its effects on lowering the total cholesterol and LDL, and increasing HDL. These results suggested that kenari nuts may be beneficial for the prevention of coronary disease.

Keywords: Kenari nut; Serum cholesterol; LDL; HDL

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